ChemicalBook > CAS DataBase List > [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone

Product Name
[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone
CAS No.
845614-11-1
Chemical Name
[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone
Synonyms
RG1678;RG1679;RO4917838;Bitopertin;Paliflutine;RG1678, RO-4917838;Palufidine,RG-1678;Bitopertin (RG-1678;inhibit,Bitopertin,RG 1678,RO-4917838,RG-1678,GlyT,Inhibitor,RO 4917838,Glycine transporters;(S)-[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone
CBNumber
CB12546501
Molecular Formula
C21H20F7N3O4S
Formula Weight
543.46
MOL File
845614-11-1.mol
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[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Property

Boiling point:
635.1±55.0 °C(Predicted)
Density 
1.444
storage temp. 
Store at -20°C
solubility 
insoluble in H2O; ≥17.94 mg/mL in EtOH; ≥88.9 mg/mL in DMSO with ultrasonic
form 
crystalline solid
pka
3.57±0.39(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19896
Product name
Bitopertin
Purity
≥98%
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
19896
Product name
Bitopertin
Purity
≥98%
Packaging
25mg
Price
$287
Updated
2024/03/01
Cayman Chemical
Product number
19896
Product name
Bitopertin
Purity
≥98%
Packaging
50mg
Price
$543
Updated
2024/03/01
Cayman Chemical
Product number
19896
Product name
Bitopertin
Purity
≥98%
Packaging
100mg
Price
$961
Updated
2024/03/01
TRC
Product number
B591450
Product name
Bitopertin
Packaging
50mg
Price
$5225
Updated
2021/12/16
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[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Chemical Properties,Usage,Production

Uses

Bitopertin is a potent and noncompetitive glycine reuptake inhibitor (GRI). Bitopertin is an investigational agent for the treatment of schizophrenia.

[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Preparation Products And Raw materials

Raw materials

Preparation Products

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[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone Suppliers

Canada 1 China 63 India 2 United States 10 Global 76
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
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+1 (866) 333-9607
Email
info@adooq.com
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United States
ProdList
2784
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58
Musechem
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+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
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4662
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InvivoChem
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+1-708-310-1919 +1-13798911105
Fax
708-557-7486
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sales@invivochem.cn
Country
United States
ProdList
6393
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Aladdin Scientific
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+1-833-552-7181
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sales@aladdinsci.com
Country
United States
ProdList
57511
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TargetMol Chemicals Inc.
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+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
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845614-11-1, [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanoneRelated Search:


  • [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone
  • Paliflutine
  • Palufidine,RG-1678
  • RG1678
  • Bitopertin
  • RO4917838
  • RG1679
  • (S)-[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone
  • Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1S)-2,2,2-trifluoro-1-methylethoxy]phenyl]-
  • RG1678, RO-4917838
  • Bitopertin (RG-1678
  • (S)-(4-(3-Fluoro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(5-(methylsulfonyl)-2-((1,1,1-trifluoropropan-2-yl)oxy)phenyl)methanone
  • inhibit,Bitopertin,RG 1678,RO-4917838,RG-1678,GlyT,Inhibitor,RO 4917838,Glycine transporters
  • 845614-11-1
  • C21H20F7N3O4S
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds